Dr. Codd Was Right: Drug Addicted

Vaccinated ≠ Not Infectious

$536,800,000 MARF^™(party like it's 1829)
-- New York Slammers, so far/2024 [GA and The Feds still to come]

Covid-19 has killed at least 1,123,836 people (as of 20 March 2023, final update)

Scientists aren't vocal enough about science. There are large groups of people who think scientists are all frauds and who don't believe in science, and they're being cultured by some of our far right-wing politicians, religious leaders and community leaders.
-- Drew Weissman/2022

To date, Microsoft is stating that organizations testing In-Memory OLTP have seen transaction speeds improve by up to 30 times compared to past performance, with the best performance gains achieved when the business logic resides in the database and not in the applications.
-- Jonathan Watts/2015 [my emphasis]

I have had to explain and re-explain and re-explain and re-explain, you know, how relational databases work, what is an eigenvector, what is dimensionality reduction.

-- Christopher Wylie/2018

... but Flash-based storage has such a different performance profile from rotating media, that I suspect that it will end up having a large impact on filesystem design. Right now, most filesystems tend to be designed with the latencies of rotating media in mind.

-- Linus Torvalds/2007

I believe quite strongly that, if you think about the issue at the appropriate level of abstraction, you're inexorably led to the position that databases must be relational.

-- Chris Date/2009

This week's thought

Investigative reporters are an idiosyncratic breed of journalist. Typically fearless, they are often a source of angina to their editors. Mr. Walsh was no exception.
-- Michael S. Rosenwald/2024 [no surprise - I spent a bit of time on Jack Anderson's staff]

Therefore:

In a time of SSD, multi-core/processor, two terabyte memory and Optane App Direct Mode machines, there is no reason not to build from BCNF data. Time to do what Dr. Codd demonstrated. Technology has finally caught up with the maths.

19 January 2020

Drug Addicted

A brand new bit of news that explains, yet again, where that $2 billion figure comes from. Drug companies that keep throwing good money after bad really, really have to be punished in such a way that doesn't punish the rest of us.

Spectrum Pharmaceuticals Inc. shares fell 47% in premarket trade Thursday after the company said a mid-stage trial of a treatment for non-small cell lung cancer, or NSCLC, missed its main goal. The Henderson, Nevada-based company said the phase 2 trial dubbed Zenith20 evaluating poziotinib in previously treated NSCLC patients was not met in the first group of 115 patients receiving 15 mg a day. "While the response rate of Cohort 1 in this trial was lower than we expected, the positive signals observed for this cohort provide support for the continued clinical evaluation of poziotinib in this patient population with significant unmet medical need," Chief Executive Joe Turgeon said in a statement.
[my emphasis]

Note that history shows that Phase 3 trials always do poorer than preceding trials.

Dr. Codd Was Right

Vaccinated ≠ Not Infectious

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19 January 2020

Drug Addicted

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